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Institute of Biotechnology
P.O.Box 56
(Visiting address: Viikinkaari 9)
00014 University of Helsinki
Finland

Tel +358 2941 59358
Fax +358 2941 59366

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Identity Code: FI-03134717

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Research

The research of the laboratory focuses on structure, function and interactions of biological macromolecules, mainly proteins, as well as on development of NMR methodology.


Recent structure: EspFU

EspFU

insulin receptor tyrosine kinase substrate (IRTKS) SH3 domain in complex with a repeat from Escherichia coli-secreted protein F-like protein encoded on prophage U (EspFU), a translocated effector of enterohemorrhagic E. coli that commandeers the mammalian actin assembly machinery.

Recent structure: MANF

MANF

Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects neurons and repairs the Parkinson disease-like symptoms in a rat 6-hydroxydopamine model.

Equipment

Varian 800MHz

We are equipped with 850 and 600 MHz spectrometers.

Recent publications

Research interests

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