DNA Sequencing and Genomics
Tel +358 (0) 2941 58884
Sequencing service e-mail:
Institute of Biotechnology
DNA Sequencing and Genomics lab
The DNA Sequencing and Genomics lab is closed on week 29 (11 - 15 July 2016).
No sequencing samples can be submitted for sequencing during this time.
We are part of the Institute of Biotechnology, an independent research unit of the University of Helsinki. We are situated in the Viikki campus in eastern Helsinki. Viikki is one of the biggest university centers in Scandinavia concentrating on various biological sciences. Our laboratory is in the Cultivator 2 building.
The laboratory was founded in 2008 by fusing two existing laboratories (DNA sequencing laboratory, founded 1990 and DNA microarray laboratory, founded 2000) into one larger unit. Our group has two distinct functions. 1) We are a core facility providing DNA sequencing service. 2) We perform research projects on several topics ranging from bioinformatics to de novo genome sequencing of entire genomes.
We have been involved in several EST projects using our Sanger sequencing high-throughput line and also finished several bacterial de novo genome projects. Moreover, the ever-developing NGS technologies have allowed us to enter high throughput sequencing of eukaryotes recently.
In 2013 we acquired the first of our two Illumina MiSeq next-generation sequencers. We have used the MiSeq for bacterial genome sequencing projects utilizing mostly a hybrid approach combining short read technology with the longer Sanger reads. The latest acqusitions of the laboratory include an Illumina NextSeq as well as a Pacific Biosciences RSII sequencer.
With our increasing interest on structures of genomes and genes we are also working on bioinformatics related to genome sequencing and assembly. A natural continuation of the assembly is the annotation of genomes which we are working on together with our collaborators. Also reseqeuncing novel strains of genomes or selected regions can be performed.