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Osamu Shimmi Group
Contact Group Leader Institute of Biotechnology Telephone
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Bone morphogenetic
protein signaling in the Drosophila development
Our group studies the function of TGF-beta type ligands in the
Drosophila development. We have recently demonstrated
that one of the TGF-beta type ligands, BMPs form heterodimers
and BMP heterodimers are key for dorso-ventral axis formation
in the early Drosophila embryo, and wing crossvein formation.
We are currently working to obtain the evidence that BMP heterodimer
is physiologically functional in vivo and to characterize
how BMP heterodimer signal is produced.
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