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University of Helsinki Institute of Biotechnology
 
Institute of Biotechnology
Osamu Shimmi Group

Group Leader
Osamu Shimmi
Tel: +358-9-191 58758
E-mail: osamu -dot- shimmi
-at- helsinki -dot- fi

Institute of Biotechnology
Street address: Viikinkaari 1 (P.O.Box 65)
00014 University of Helsinki
Finland
Tel: +358-9-1911
fax +358-9-1915 9366

Business Identity Code:
FI-03134717
(University of Helsinki)

Institute of Biotechnology

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Bone morphogenetic protein signaling in the Drosophila development

Our group studies the function of TGF-beta type ligands in the Drosophila development. We have recently demonstrated that one of the TGF-beta type ligands, BMPs form heterodimers and BMP heterodimers are key for dorso-ventral axis formation in the early Drosophila embryo, and wing crossvein formation. We are currently working to obtain the evidence that BMP heterodimer is physiologically functional in vivo and to characterize how BMP heterodimer signal is produced.