|Functional analysis of the yeast
genome: Unknown genes and alpha-galactosidase -encoding
of General Microbiology
We participate among over 100 European laboratories in the functional analysis of systematically sequenced 1000 unknown genes of the yeast Saccharomyces cerevisiae (EUROFAN project). Our task is to delete 6 genes and study the effects of the deletions on certain functions of the yeast cell: nutrition, growth, sexual reproduction. We also clone the deleted gene cassettes and the original (cognate) genes for use in international collaboration.
The alpha-galactosidase -encoding MEL gene studies in Saccharomyces yeasts focus on aspects of gene expression, molecular evolution and taxonomy, and yeast physiology.
Hilkka Turakainen, Ph. D.; Marja Aittamaa, M. Sc.
Turakainen, H., Aho, S. and Korhola, M. MEL gene polymorphism in the genus Saccharomyces. Appl. Environm. Microbiol., 59: 2622-2630, 1993.
Turakainen, H., Kristo, P. and Korhola, M. Consideration of the evolution of the Saccharomyces cerevisiae MEL gene family on the basis of the nucleotide sequences of the genes and their flanking regions. YEAST, 10: 1559-1568, 1994.
Naumova, E.S., Turakainen, H., Naumov, G.I. and Korhola, M. Superfamily of alpha-galactosidase MEL genes of the Saccharomyces sensu stricto complex. Mol. Gen. Genet., 135: 111-117, 1996.
Paalme, T., Elken, R., Vilu, R. and Korhola, M. Growth efficiency of Saccharomyces cerevisiae on glucose/ethanol media with smooth change in dilution rate (A-stat). Enzyme Microbal. Technol., 20: 174-181, 1997.
Codůn, A.C., Ben&146tez, T. and Korhola, M. Chromosomal polymorphism and adaptation to specific industrial environments of Saccharomyces strains. Appl. Microbiol. Biotechnol., 49, No. 2: 154-163, 1998.
Alkomohr Biotech Ltd., European Commission, private foundations, Technology Development Centre of Finland (TEKES)
|Last update 01.07.1998||Maintained by Jari Ylšnne (firstname.lastname@example.org)|